How much nicotine is in a cigarette compared to a vape? Vaping The Guardian 1 standard vape pod does not directly equal 20 packs of cigarettes in terms of nicotine content, but it can contain nicotine equivalent to a pack of cigarettes. A JUUL pod, for Exclusive FDA Authorizes Juul's E Cigarettes After Ban Nearly Bankrupted Firm WSJ DYKOne Juul pod contains as much nicotine as a pack of cigarettes. Side effects include increased heart rate and blood pressure, lung disease, chronic bronchitis and insulin resistance leading to type 2